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Proteins and Peptides

BDNF (R129A, R130A) Protein (His Tag)

Product Sizes
100 ug
£600.00
M60-005-L100-100UG
About this Product
SKU:
M60-005-L100
Additional Names:
Bdnf Protein
Buffer:
PBS
Extra Details:
BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Formulation:
lyophilized
Molecular Weight:
27.4 kDa
Purity:
>95%
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins