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Proteins and Peptides

IL-13

Product Sizes
2 ug
£178.82
M10-071-2UG
10 ug
£307.06
M10-071-10UG
About this Product
SKU:
M10-071
Additional Names:
Il13; Il-13
Buffer:
10 mM sodium citrate pH 4.0
translate.label.attr.clone:
(#5J48)
Extra Details:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1B Beta, TNF-A Alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.
Formulation:
lyophilized
Host:
Mouse
Molecular Weight:
12.3 kDa
Purity:
> 98% by SDS-PAGE & HPLC analyses
Reactivities:
Human, Mouse
Sequence:
MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins