BD-3 (Animal Free)
Product Sizes
20 ug
£367.06
M10-023-AF-20UG
About this Product
- SKU:
- M10-023-AF
- Additional Names:
- Beta-Defensin 3, DEFB3, DEFB103A
- translate.label.attr.clone:
- (#21Q2)
- Extra Details:
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, six human B Beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. B Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-3 is a 4.6 kDa protein containing 41 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Rat
- Molecular Weight:
- 4.6 kDa
- Purity:
- ≥98%
- Reactivities:
- Mouse
- Sequence:
- KKINNPVSCL RKGGRCWNRC IGNTRQIGSC GVPFLKCCKR K
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins