IL-6
Product Sizes
5 ug
£147.06
M10-017-5UG
20 ug
£307.06
M10-017-20UG
About this Product
- SKU:
- M10-017
- Additional Names:
- Il6; Il-6
- Buffer:
- 50 mM Acetic Acid
- translate.label.attr.clone:
- (#9D24)
- Extra Details:
- IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R A Alpha and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Rat
- Molecular Weight:
- 21.7 kDa
- Purity:
- > 98% by SDS-PAGE & Coomassie stain
- Reactivities:
- Fish, Mouse, Non-human Primate, Rat
- Sequence:
- MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins