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Proteins and Peptides

BD-2 (SAP1)

Product Sizes
5 ug
£178.82
M10-008-5UG
20 ug
£307.06
M10-008-20UG
About this Product
SKU:
M10-008
Additional Names:
Beta-Defensin 2, DEFB2, DEFB4A, Skin-Antimicrobial Peptide 1, SAP1
translate.label.attr.clone:
(#12J21)
Extra Details:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, six human B Beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. B Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-2 is a 5.5 kDa protein containing 51 amino acid residues.
Formulation:
lyophilized
Host:
Mouse
Molecular Weight:
5.5 kDa
Purity:
> 98% by SDS-PAGE & HPLC analyses
Reactivities:
Mouse
Sequence:
AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins