BD-2 (SAP1)
Product Sizes
5 ug
£178.82
M10-008-5UG
20 ug
£307.06
M10-008-20UG
About this Product
- SKU:
- M10-008
- Additional Names:
- Beta-Defensin 2, DEFB2, DEFB4A, Skin-Antimicrobial Peptide 1, SAP1
- translate.label.attr.clone:
- (#12J21)
- Extra Details:
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, six human B Beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. B Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-2 is a 5.5 kDa protein containing 51 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Mouse
- Molecular Weight:
- 5.5 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Mouse
- Sequence:
- AVGSLKSIGY EAELDHCHTN GGYCVRAICP PSARRPGSCF PEKNPCCKYM K
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins