OX-40L / TNFSF4 / CD252 Protein (ECD,mFc Tag)
Product Sizes
1000 ug
£2494.00
600-302-L1000-1000UG
About this Product
- SKU:
- 600-302-L1000
- Additional Names:
- CD134L Protein; CD252 Protein; GP34 Protein; OX-40L Protein; OX4OL Protein; TNLG2B Protein; TXGP1 Protein
- Buffer:
- PBS
- Extra Details:
- OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD4-stimulated B cells, this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
- Formulation:
- lyophilized or frozen liquid
- Molecular Weight:
- 53 kDa (glycosylated)
- Purity:
- >90%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
