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Proteins and Peptides

GITR Protein (His & AVI Tag), Biotinylated

Product Sizes
20 ug
£494.00
600-283-L20-20UG
About this Product
SKU:
600-283-L20
Additional Names:
AITR Protein; CD357 Protein; ENERGEN Protein; GITR Protein; GITR-D Protein; UNQ319/PRO364 Protein
Buffer:
PBS
Extra Details:
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
Formulation:
lyophilized
Molecular Weight:
29 kDa (glycosylated)
Purity:
>95%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins