GITR / TNFRSF18 Protein (hFc Tag)
Product Sizes
1000 ug
£2129.00
600-281-L1000-1000UG
About this Product
- SKU:
- 600-281-L1000
- Additional Names:
- AITR Protein; Gitr Protein; Tnfrsf18 Protein
- Buffer:
- PBS
- Extra Details:
- GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
- Formulation:
- lyophilized or frozen liquid
- Molecular Weight:
- 96 kDa and 45 kDa (glycosylated)
- Purity:
- ≥90%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
