Thrombomodulin / THBD Protein (His Tag)
Product Sizes
50 ug
£459.00
600-256-L50-50UG
About this Product
- SKU:
- 600-256-L50
- Additional Names:
- AHUS6 Protein; BDCA-3 Protein; BDCA3 Protein; CD141 Protein; THPH12 Protein; THRM Protein; TM Protein
- Buffer:
- PBS
- Extra Details:
- Thrombomodulin, also known as THBD (CD141), is an integral membrane protein that reduces blood coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is expressed on the surface of endothelial cells and serves as a cofactor for thrombin. It is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. Thrombomodulin also regulates C3b inactivation by factor I. Mutations in the thrombomodulin gene have also been reported to be associated with atypical hemolytic-uremic syndrome.
- Formulation:
- lyophilized
- Molecular Weight:
- 54 kda
- Purity:
- ≥90%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
