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Proteins and Peptides

TGF-beta 3 / TGFB3 Protein (hFc Tag)

Product Sizes
1000 ug
£3341.00
600-255-L1000-1000UG
About this Product
SKU:
600-255-L1000
Additional Names:
ARVD Protein; ARVD1 Protein; LDS5 Protein; RNHF Protein; TGF-beta3 Protein
Buffer:
20 mM HEPES, 150 mM NaCl, 0.2% CHAPS, pH 7.0.
Extra Details:
Transforming growth factor (TGF) beta 3 is a member of the TGF-B Beta superfamily and regulates diverse cellular phenotypes. TGF-beta 3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massague; McDowell et al.). TGF-beta 3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall et al.; Holton et al.). TGF-beta 3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of fibroblast growth factors 2 and 18 (James et al.).
Formulation:
lyophilized or frozen liquid
Molecular Weight:
42 kDa
Purity:
>90%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins