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Proteins and Peptides

NRG1-alpha Protein (ECD, His Tag)

Product Sizes
1000 ug
£2506.00
600-208-L1000-1000UG
About this Product
SKU:
600-208-L1000
Additional Names:
ARIA Protein; GGF Protein; GGF2 Protein; HGL Protein; HRG Protein; HRG1 Protein; HRGA Protein; MST131 Protein; MSTP131 Protein; NDF Protein; NRG1-IT2 Protein; SMDF Protein
Buffer:
PBS
Extra Details:
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis.
Formulation:
lyophilized or frozen liquid
Molecular Weight:
45 kDa (glycosylated)
Purity:
>98%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins