B Beta-NGF / Beta-NGF Protein
Product Sizes
100 ug
£353.00
600-195-L100-100UG
About this Product
- SKU:
- 600-195-L100
- Additional Names:
- Beta-NGF Protein; HSAN5 Protein; NGFB Protein
- Buffer:
- 40mM His, 40mM Arg, 150mM NaCl, pH 5.5
- Extra Details:
- Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, A Alpha, B Beta, and G Gamma, among which, the B Beta subunit, called B Beta-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
- Formulation:
- lyophilized
- Molecular Weight:
- 30 kDa
- Purity:
- ≥ 95 % as determined by SDS-PAGE, ≥ 90 % as determined by SEC-HPLC, ≥ 90% as determined by SEC-MALS
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
