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Proteins and Peptides

PBEF / Visfatin / NAMPT Protein (His & GST Tag)

Product Sizes
50 ug
£388.00
600-194-L50-50UG
About this Product
SKU:
600-194-L50
Additional Names:
1110035O14Rik Protein; PBEF Protein; PBEF1 Protein; VF Protein; VISFATIN Protein
Buffer:
20mM Tris, 500mM NaCl, pH 8.0, 20% gly, 0.3mM DTT
Extra Details:
Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is also considered as an essential enzyme mediating granulocyte colony-stimulating factor (G-CSF)-triggered granulopoiesis in healthy individuals and individuals with severe congenital neutropenia. Intracellular NAMPT and NAD+ amounts in myeloid cells, as well as plasma NAMPT and NAD+ levels, were increased by G-CSF treatment of both healthy volunteers and individuals with congenital neutropenia.
Formulation:
lyophilized
Molecular Weight:
75 kDa
Purity:
≥ 90 % as determined by SDS-PAGE. ≥ 80 % as determined by SEC-HPLC.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins