CD86 / B7-2 Protein (hFc Tag)
Product Sizes
1000 ug
£1682.00
600-061-L1000-1000UG
About this Product
- SKU:
- 600-061-L1000
- Additional Names:
- B7-2 Protein; B7.2 Protein; B70 Protein; CD28LG2 Protein; LAB72 Protein
- Buffer:
- PBS
- Extra Details:
- CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.
- Formulation:
- lyophilized or frozen liquid
- Molecular Weight:
- 51.9 kDa
- Purity:
- ≥90%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
