CCL24 / Eotaxin-2 / MPIF-2 Protein (His Tag)
Product Sizes
1000 ug
£2929.00
600-037-L1000-1000UG
About this Product
- SKU:
- 600-037-L1000
- Additional Names:
- Ckb-6 Protein; eotaxin-2 Protein; MPIF-2 Protein; MPIF2 Protein; SCYA24 Protein
- Buffer:
- 20 mM Tris, 500 mM NaCl, 10 % Glycerol, pH 7.4
- Extra Details:
- CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.
- Formulation:
- lyophilized or frozen liquid
- Molecular Weight:
- 11.8 kDa
- Purity:
- >90%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
