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Antibodies

Lyve-1

Product Sizes
100 ug
£270.59
103-PA50-100UG
200 ug
£411.76
103-PA50-200UG
About this Product
SKU:
103-PA50
Additional Names:
Lyve1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
(#4A37)
Clonality:
Polyclonal
Extra Details:
LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Formulation:
lyophilized
Host:
Rabbit
Immunogen:
Recombinant mouse soluble Lyve-1 (RT#S01-026)
Purification:
Protein A Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Polyclonal Antibody