VCAM-1
Product Sizes
100 ug
£674.12
103-M98-100UG
About this Product
- SKU:
- 103-M98
- Additional Names:
- CD106; Vascular Cell Adhesion Protein 1; V-CAM 1
- Application:
- IHC-Paraffin, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- MAB0804
- Clonality:
- Monoclonal
- Extra Details:
- The antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- Cytokine stimulated mouse endothelial cells
- Isotype:
- IgG1
- Purification:
- Protein A/G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody