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Antibodies

VCAM-1

Product Sizes
100 ug
£674.12
103-M98-100UG
About this Product
SKU:
103-M98
Additional Names:
CD106; Vascular Cell Adhesion Protein 1; V-CAM 1
Application:
IHC-Paraffin, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
MAB0804
Clonality:
Monoclonal
Extra Details:
The antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
Formulation:
lyophilized
Host:
Rat
Immunogen:
Cytokine stimulated mouse endothelial cells
Isotype:
IgG1
Purification:
Protein A/G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody