TNFSF11 beta
Product Sizes
100 ug
£674.12
103-M560-100UG
About this Product
- SKU:
- 103-M560
- Additional Names:
- Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor (ODF); Osteoprotegerin ligand (OPGL), Receptor activator of nuclear factor kappa-B ligand (RANKL), TNF-related activation-induced cytokine (TRANCE)
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7F37
- Clonality:
- Monoclonal
- Extra Details:
- RANKL ("Receptor Activator of NF-K KappaB Ligand") is a protein of the tumor necrosis factor (TNF) family discovered in 1997 that is significantly involved in the regulation of bone remodeling. The protein is also known as TRANCE (TNF-related activation-induced cytokine), CD254, OPGL, and ODF. RANKL is secreted by, among others, osteoblasts (cells that build bone substance) and binds to the "matching" receptor RANK of monocytic osteoclast progenitor cells, inducing their differentiation into osteoclasts (cells that degrade bone substance again). The RANK/RANKL system is a biochemical regulatory circuit that causes bone resorption to remain in healthy balance with bone formation, which is a prerequisite for the dynamic architecture of the bone system. This system can be disturbed in various diseases and is therefore of practical interest to medicine. Translated with www.DeepL.com/Translator (free version)
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- Mouse recombinant protein TNFSF11
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody