IL-6R alpha
Product Sizes
100 ug
£674.12
103-M544-100UG
About this Product
- SKU:
- 103-M544
- Additional Names:
- Il6; Il-6
- Application:
- Flow Cytometry, Immunocytochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 27E22
- Clonality:
- Monoclonal
- Extra Details:
- IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R A Alpha and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant mouse IL-6R alpha
- Isotype:
- IgG2
- Purification:
- Protein A/G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody