IL-1 R4
Product Sizes
100 ug
£674.00
103-M536-100UG
About this Product
- SKU:
- 103-M536
- Additional Names:
- IL-1 R, DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7K14
- Clonality:
- Monoclonal
- Extra Details:
- The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. ST2L, also known as IL-1 R4, is a transmembrane glycoprotein in the interleukin-1 receptor family. ST2L is expressed on mast cells and Th2 cells as well as on stressed cardiac myocytes and airway epithelia. ST2L associates with IL-1R AcP to form a receptor complex for IL-33. Alternative splicing generates ST2, a secreted isoform that functions as an inhibitor of IL-33 signaling. Within the ECD, mouse ST2L shares 68% aa sequence identity with human ST2L.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- Recombinant mouse IL-1R4
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody
