CXCR4
Product Sizes
100 ug
£674.12
103-M522-100UG
About this Product
- SKU:
- 103-M522
- Additional Names:
- C-X-C chemokine receptor type 4, CXC-R4; CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor (LESTR), Pre-B-cell-derived chemokine receptor (PB-CKR), Stromal cell-derived factor 1 receptor (SDF-1 receptor)
- Application:
- Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 30L4
- Clonality:
- Monoclonal
- Extra Details:
- CXCR4 (short for CXC motif chemokine receptor 4) is a receptor protein of the chemokine receptor family. CXCR4 is common in many cells of the hematopoietic system and is expressed in particular by many stem cells and tumor cells. This receptor is activated by the chemokine CXCL12 and the cytokine macrophage migration inhibitory factor (MIF). CXCR4 plays a key role in the mobilization and targeted migration of stem cells to their storage (e.g., fetal liver, bone marrow) or their sites of use in organ formation (organogenesis) and organ and wound healing. Pathophysiologically, CXCR4 is involved in tumor growth and metastatic spread as well as inflammatory processes. In addition, CXCR4 is the primary co-receptor for T cell-using (T-tropic) HI viruses.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- Mouse recombinant CXCR4
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody