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Antibodies

CXCR4

Product Sizes
100 ug
£674.12
103-M522-100UG
About this Product
SKU:
103-M522
Additional Names:
C-X-C chemokine receptor type 4, CXC-R4; CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor (LESTR), Pre-B-cell-derived chemokine receptor (PB-CKR), Stromal cell-derived factor 1 receptor (SDF-1 receptor)
Application:
Flow Cytometry, Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
30L4
Clonality:
Monoclonal
Extra Details:
CXCR4 (short for CXC motif chemokine receptor 4) is a receptor protein of the chemokine receptor family. CXCR4 is common in many cells of the hematopoietic system and is expressed in particular by many stem cells and tumor cells. This receptor is activated by the chemokine CXCL12 and the cytokine macrophage migration inhibitory factor (MIF). CXCR4 plays a key role in the mobilization and targeted migration of stem cells to their storage (e.g., fetal liver, bone marrow) or their sites of use in organ formation (organogenesis) and organ and wound healing. Pathophysiologically, CXCR4 is involved in tumor growth and metastatic spread as well as inflammatory processes. In addition, CXCR4 is the primary co-receptor for T cell-using (T-tropic) HI viruses.
Formulation:
lyophilized
Host:
Rat
Immunogen:
Mouse recombinant CXCR4
Isotype:
IgG2
Purification:
Protein G Purified
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody