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Antibodies

Wnt-3a

Product Sizes
100 ug
£674.12
103-M501-100UG
About this Product
SKU:
103-M501
Additional Names:
Wnt3a; vt; Wnt-3a
Application:
Block/Inhibit/Neutralise, Western Blot
Buffer:
PBS
translate.label.attr.clone:
13F9
Clonality:
Monoclonal
Extra Details:
Wnt-4 is a 38 - 42 kDa member of the Wnt family of secreted glycoproteins, which act as short-range signaling molecules via Frizzled receptors and a cascade of intracellular signals in vertebrate embryogenesis. Wnt-4 has been shown to play a critical role in the development of the reproductive system and in the formation of the kidneys, adrenals, pituitary gland, and mammary tissues. In the development of the reproductive system, Wnt-4 expression is down-regulated in the developing gonad after E11.5, although it persists in the developing ovary. Targeted deletion of Wnt-4 results in masculinization of XX mice, with rudimentary development of the masculine internal (Wolffian) ducts and degeneration of the female (Mullerian) reproductive tract. In addition to its involvement in urogenital development, Wnt-4 is also expressed in the perichondrium of the long bones, and promotes osteoblast differentiation. Wnt-4 may also be associated with abnormal proliferation in human breast tissue.
Formulation:
lyophilized
Host:
Rat
Immunogen:
recombinant protein of Wnt-3a
Isotype:
IgG2
Purification:
Protein G/A chromatography
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody