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Antibodies

Semaphorin 6B

Product Sizes
100 ug
£674.12
103-M464-100UG
About this Product
SKU:
103-M464
Additional Names:
Sema6b; VIb; Sema; Seman; semaZ
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
4N68
Clonality:
Monoclonal
Extra Details:
The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.
Formulation:
lyophilized
Host:
Rat
Immunogen:
Mouse recombinant protein of Semaphorin 6B EC domain
Isotype:
IgG2
Purification:
Protein A/G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody