Resistin
Product Sizes
100 ug
£674.12
103-M461-100UG
About this Product
- SKU:
- 103-M461
- Additional Names:
- Retn; ADSF; Rstn; Xcp4; Fizz3
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 5B54
- Clonality:
- Monoclonal
- Extra Details:
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-A Alpha and RELM-B Beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant mouse Resistin
- Isotype:
- IgG1
- Purification:
- Protein A/G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody