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Antibodies

IL-28B

Product Sizes
100 ug
£674.12
103-M419-100UG
About this Product
SKU:
103-M419
Additional Names:
Il28b; Il28; IFL-1; IL-28B; INF-alpha; INF-lambda
Application:
Block/Inhibit/Neutralise, Western Blot
Buffer:
PBS
translate.label.attr.clone:
23A14
Clonality:
Monoclonal
Extra Details:
Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
Formulation:
lyophilized
Host:
Rat
Immunogen:
recombinant mouse IL-2(B
Isotype:
IgG2
Purification:
Protein A/G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody