IL-1 alpha
Product Sizes
100 ug
£674.12
103-M402-100UG
About this Product
- SKU:
- 103-M402
- Additional Names:
- Il1a; Il-1a
- Application:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 9M44
- Clonality:
- Monoclonal
- Extra Details:
- Interleukin-1 (IL-1) is a name that designates two proteins, IL-1 alpha and IL-1 beta, which are the products of distinct genes, but which show approximately 25% amino acid sequence identity and which recognize the same cell surface receptors. Although IL-1 production is generally considered to be a consequence of inflammation, recent evidence suggests that IL-1 is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen. Cells in particular known to produce IL-1 include osteoblasts, monocytes, macrophages, keratinocytes, Kupffer cells, hepatocytes, thymic and salivary gland epithelium, Schwann cells, fibroblasts and glia (oligodendroglia, astrocytes and microglia).
- Formulation:
- lyophilized
- Host:
- Hamster
- Immunogen:
- recombinant mouseIL-1 alpha
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody