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Antibodies

Cathepsin E

Product Sizes
100 ug
£674.12
103-M316-100UG
About this Product
SKU:
103-M316
Additional Names:
Ctse; CE; CatE; A430072O03Rik; C920004C08Rik
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
7J15
Clonality:
Monoclonal
Extra Details:
Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsins D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving the Swedish mutant of amyloid precursor protein (APP) at the B Beta site but show almost no reactivity with the wildtype APP. Mouse Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (residues 1-18), a propeptide (residues 19-59), and a mature chain (residues 60-397).
Formulation:
lyophilized
Host:
Rat
Immunogen:
recombinant mouse Cathepsin-E
Isotype:
IgG2
Purification:
Protein G/A chromatography
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody