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Antibodies

ALS

Product Sizes
100 ug
£674.12
103-M304-100UG
About this Product
SKU:
103-M304
Additional Names:
Igfals; ALS; Albs; mKIAA4111
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
4K23
Clonality:
Monoclonal
Extra Details:
ALS (Acid labile subunit) is an 84-86 kDa glycoprotein member of the leucine rich repeat superfamily of molecules. It is secreted by hepatocytes in response to growth hormone stimulation, and forms a 140-150 kDa ternary complex with IGFBP3 (or IGFBP5) and IGFI. This complex increases the half-life of IGFI and retains it in the circulation for use in multiple tissues. Mature mouse ALS is 580 amino acids (aa) in length (aa 24-603). It contains twentyone 20-23 aa LRRs that participate in proteinprotein interactions. There are two potential isoform variants that show N-terminal extensions. One contains a 66 aa substitution for aa 1 -5, while another possesses an 89 aa substitution again for aa 15. Over aa 28-603, mouse ALS shares 79% and 93% aa identity with human and rat ALS, respectively.
Formulation:
lyophilized
Host:
Rat
Immunogen:
recombinant protein of ALS
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody