ALS
Product Sizes
100 ug
£674.12
103-M304-100UG
About this Product
- SKU:
- 103-M304
- Additional Names:
- Igfals; ALS; Albs; mKIAA4111
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 4K23
- Clonality:
- Monoclonal
- Extra Details:
- ALS (Acid labile subunit) is an 84-86 kDa glycoprotein member of the leucine rich repeat superfamily of molecules. It is secreted by hepatocytes in response to growth hormone stimulation, and forms a 140-150 kDa ternary complex with IGFBP3 (or IGFBP5) and IGFI. This complex increases the half-life of IGFI and retains it in the circulation for use in multiple tissues. Mature mouse ALS is 580 amino acids (aa) in length (aa 24-603). It contains twentyone 20-23 aa LRRs that participate in proteinprotein interactions. There are two potential isoform variants that show N-terminal extensions. One contains a 66 aa substitution for aa 1 -5, while another possesses an 89 aa substitution again for aa 15. Over aa 28-603, mouse ALS shares 79% and 93% aa identity with human and rat ALS, respectively.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant protein of ALS
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody