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Antibodies

Toll-like Receptor 2 (TLR2)

Product Sizes
100 ug
£674.12
103-M278-100UG
About this Product
SKU:
103-M278
Additional Names:
Tlr2; Ly105
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
5B57
Clonality:
Monoclonal
Extra Details:
TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.
Formulation:
lyophilized
Host:
Rat
Immunogen:
mouse recombinant protein of the EC-domain of TLR2
Isotype:
IgG2
Purification:
Protein A/G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody