Toll-like Receptor 2 (TLR2)
Product Sizes
100 ug
£674.12
103-M278-100UG
About this Product
- SKU:
- 103-M278
- Additional Names:
- Tlr2; Ly105
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 5B57
- Clonality:
- Monoclonal
- Extra Details:
- TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- mouse recombinant protein of the EC-domain of TLR2
- Isotype:
- IgG2
- Purification:
- Protein A/G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody