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Antibodies

T-cell Immunoglobulin Mucin-3 (TIM-3)

Product Sizes
100 ug
£674.12
103-M276-100UG
About this Product
SKU:
103-M276
Additional Names:
Havcr2; Tim3; TIM-3; Timd3
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
6F46
Clonality:
Monoclonal
Extra Details:
T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 aa mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 aa extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD. One splice variant of TIM-3 is truncated within the mucin domain and presumably is secreted.
Formulation:
lyophilized
Host:
Rat
Immunogen:
mouse recombinant protein of TIM-3
Isotype:
IgG2
Purification:
Protein A/G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody