Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

IL-1 R4

Product Sizes
100 ug
£674.12
103-M272-100UG
About this Product
SKU:
103-M272
Additional Names:
IL-1 R, DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
3F22
Clonality:
Monoclonal
Extra Details:
The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. ST2L, also known as IL-1 R4, is a transmembrane glycoprotein in the interleukin-1 receptor family. ST2L is expressed on mast cells and Th2 cells as well as on stressed cardiac myocytes and airway epithelia. ST2L associates with IL-1R AcP to form a receptor complex for IL-33. Alternative splicing generates ST2, a secreted isoform that functions as an inhibitor of IL-33 signaling. Within the ECD, mouse ST2L shares 68% aa sequence identity with human ST2L.
Formulation:
lyophilized
Host:
Rat
Immunogen:
recombinant mouse IL-1R4
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody