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Antibodies

LPAM-1

Product Sizes
100 ug
£674.12
103-M176-100UG
About this Product
SKU:
103-M176
Additional Names:
LPAM-1
Application:
Flow Cytometry, IHC-Paraffin, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
2G18
Clonality:
Monoclonal
Extra Details:
The antibody is specific for a combinatorial determinate of integrin A Alpha4B Beta7complex. Integrin A Alpha4B Beta7 is composed of a 150 kD (A Alpha4 or CD49d) and a 130 kD (B Beta7) heterodimer, also known as CD49d/B Beta7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin A Alpha4B Beta7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.
Formulation:
lyophilized
Host:
Rat
Immunogen:
cell lysates of mouse lymphocytes
Isotype:
IgG2
Purification:
Protein A/G Purified
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody