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Antibodies

CD25

Product Sizes
100 ug
£674.12
103-M107-100UG
About this Product
SKU:
103-M107
Additional Names:
CD25; Il2r; Ly-43; interleukin 2 receptor, alpha chain; Il2ra
Application:
Flow Cytometry, Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
7G19
Clonality:
Monoclonal
Extra Details:
The biological effects of interleukin 2 (IL-2) are mediated by its binding to a multi-chain cellular receptor complex. The IL-2 receptor (IL-2 R) complex consists of three glycoprotein chains. The alpha chain (IL-2 R alpha /CD25) and beta chain (IL-2 R beta /CD122) act together with the gamma chain (IL-2 R gamma /CD132) to form a high affinity receptor that transduces the signal upon IL-2 binding. Alone, IL-2 R alpha binds IL-2 with low affinity, but is unable to transduce a signal. The alpha/beta combination binds IL-2 with intermediate affinity, but is still unable to transmit a signal inside the cell. The beta/gamma complex has intermediate affinity and is capable of signaling if the concentration of IL-2 is relatively high.
Formulation:
lyophilized
Host:
Rat
Immunogen:
Recombinant Mouse CD25 protein
Isotype:
IgG1
Purification:
Protein G/A chromatography
Reactivities:
Mouse
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody