CD25
Product Sizes
100 ug
£674.12
103-M107-100UG
About this Product
- SKU:
- 103-M107
- Additional Names:
- CD25; Il2r; Ly-43; interleukin 2 receptor, alpha chain; Il2ra
- Application:
- Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 7G19
- Clonality:
- Monoclonal
- Extra Details:
- The biological effects of interleukin 2 (IL-2) are mediated by its binding to a multi-chain cellular receptor complex. The IL-2 receptor (IL-2 R) complex consists of three glycoprotein chains. The alpha chain (IL-2 R alpha /CD25) and beta chain (IL-2 R beta /CD122) act together with the gamma chain (IL-2 R gamma /CD132) to form a high affinity receptor that transduces the signal upon IL-2 binding. Alone, IL-2 R alpha binds IL-2 with low affinity, but is unable to transduce a signal. The alpha/beta combination binds IL-2 with intermediate affinity, but is still unable to transmit a signal inside the cell. The beta/gamma complex has intermediate affinity and is capable of signaling if the concentration of IL-2 is relatively high.
- Formulation:
- lyophilized
- Host:
- Rat
- Immunogen:
- Recombinant Mouse CD25 protein
- Isotype:
- IgG1
- Purification:
- Protein G/A chromatography
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody