HGF
Product Sizes
50 ug
£271.00
102-PA62AG-50UG
About this Product
- SKU:
- 102-PA62AG
- Additional Names:
- HGF; SF; HGFB; HPTA; F-TCF; DFNB39
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (A Alpha-chain and B Beta-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The A Alpha-chain consists of 463 amino acid residues and four kringle domains. The B Beta-chain consists of 234 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Rabbit
- Immunogen:
- Recombinant human HGF (RT #300-011)
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody
