TNF-beta
Product Sizes
100 ug
£365.88
102-P88-100UG
About this Product
- SKU:
- 102-P88
- Additional Names:
- LTA; LT; TNFB; TNFSF1
- Application:
- Block/Inhibit/Neutralise, ELISA, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- TNF-beta, also known as lymphotoxin-alpha (LTalpha) and TNF-alpha are two structurally and functionally related proteins that bind to the same cell surface receptors (TNF RI and TNF RII) and produce a vast range of similar, but not identical effects. Mature TNF-beta/LTalpha and TNF-alpha share approximately 35% protein sequence homology, and the biologically active secreted forms of both proteins are trimers. Human and mouse TNF-beta/LTalpha share approximately 74% homology in their amino acid sequence and exhibit cross-species activity. Soluble TNF-beta/LTalpha is a homotrimer in solution. Secreted TNF-beta/LTalpha also complexes with the membrane associated LTbeta/TNFSF3 to generate two types of heterotrimers, LTalpha1/beta2 and LTalpha2/beta1.
- Formulation:
- lyophilized from PBS
- Host:
- Rabbit
- Immunogen:
- recombinant human TNF-beta
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody