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Antibodies

PDGF-BB

Product Sizes
100 ug
£365.88
102-P78-100UG
About this Product
SKU:
102-P78
Additional Names:
PDGF-BB
Application:
Block/Inhibit/Neutralise, ELISA, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet A Alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-A Alpha and PDGFR-B Beta. PDGFR-A Alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-B Beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).
Formulation:
lyophilized from PBS
Host:
Rabbit
Immunogen:
Recombinant Human PDGF-BB
Purification:
Antigen-affinity purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Polyclonal Antibody