Persephin (PSP)
Product Sizes
100 ug
£365.88
102-P247-100UG
About this Product
- SKU:
- 102-P247
- Additional Names:
- PSPN; PSP
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- Rabbit IgG
- Clonality:
- Polyclonal
- Extra Details:
- Persephin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Neurturin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system, composed of RET and one of four GFR A Alpha (A Alpha1-A Alpha4) receptors. The GFRA Alpha4 was first identified in chicken and was later shown to be the preferential binding subunit for Persephin. Persephin promotes the survival of ventral midbrain dompaminergic neurons and motor neurons after sciatic nerve oxotomy, and like GNDF, promotes ureteric bud branching. However, in contrast to GDNF and Neurturin, Persephin does not support survival of peripheral neurons.
- Formulation:
- lyophilized from PBS
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Persephin
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody