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Antibodies

PAI-1

Product Sizes
100 ug
£365.88
102-P246-100UG
About this Product
SKU:
102-P246
Additional Names:
PAI-1
Application:
Block/Inhibit/Neutralise, ELISA, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
As a member of the Serpin superfamily of serine protease inhibitors, Serpin E1/PAI1 is the principal inhibitor of urokinase-type plasminogen activator (uPA) and tissue type plasminogen activator (tPA). As important regulators of extracellular matrix remodeling, uPA and PAI 1 play a major role in many processes such as angiogenesis, tumor invasion and obesity. For example, uPA and PAI1 are the only tumor prognostic factors validated at the highest level of evidence with regard to their clinical utility in breast cancer. The human PAI1 is initially synthesized as 402 amino acid precursor with a Nterminal signal peptide. PAI 1 may exist in one of two possible conformations, designated as active or latent.
Formulation:
lyophilized from PBS
Host:
Rabbit
Immunogen:
Recombinant Human PAI-1
Purification:
Antigen-affinity purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Polyclonal Antibody