MIA
Product Sizes
100 ug
£365.88
102-P239-100UG
About this Product
- SKU:
- 102-P239
- Additional Names:
- MIA; CD-RAP
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- (#12D9)
- Clonality:
- Polyclonal
- Extra Details:
- MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis. Recombinant human MIA is a 12.2 kDa globular protein containing 108 amino acid residues including two intramolecular disulfide bonds. .
- Formulation:
- lyophilized from PBS
- Host:
- Rabbit
- Immunogen:
- Recombinant Human MIA
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody