IL-33
Product Sizes
100 ug
£366.00
102-P238-100UG
About this Product
- SKU:
- 102-P238
- Additional Names:
- IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- Rabbit IgG
- Clonality:
- Polyclonal
- Extra Details:
- IL-33 is a proinflammatory protein that may also regulate gene transcription. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines and is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1alpha or IL-1 beta stimulation. Similar to IL-1, IL-33 can be cleaved in vitro by caspase-1, generating an N-terminal fragment that is slightly shorter than the C-terminal fragment. The N-terminal portion of full length IL-33 contains a predicted bipartite nuclear localization sequence and a homeodomain-like helix-turn-helix DNA binding domain.
- Formulation:
- lyophilized from PBS
- Host:
- Rabbit
- Immunogen:
- Recombinant human IL-33
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody
