BD-4
Product Sizes
100 ug
£365.88
102-P221-100UG
About this Product
- SKU:
- 102-P221
- Additional Names:
- DEFB104A; BD-4; DEFB4; hBD-4; DEFB-4; DEFB104; DEFB104B
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- (#4D22)
- Clonality:
- Polyclonal
- Extra Details:
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, six human B Beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. B Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney. In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes.
- Formulation:
- lyophilized from PBS
- Host:
- Rabbit
- Immunogen:
- E.coli derived Recombinant Human BD-4
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody