BD-1
Product Sizes
100 ug
£365.88
102-P219-100UG
About this Product
- SKU:
- 102-P219
- Additional Names:
- DEFB1; BD1; HBD1; DEFB-1; DEFB101
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The A Alpha-defensins are distinguished from the B Beta-defensins by the pairing of their three disulfide bonds. To date, six human B Beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. B Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The B Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. B Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
- Formulation:
- lyophilized from PBS
- Host:
- Rabbit
- Immunogen:
- E.coli derived Recombinant Human BD-1 (47a.a.)
- Purification:
- Antigen-affinity purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Polyclonal Antibody