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Antibodies

Nidogen-1 (Entactin)

Product Sizes
100 ug
£674.12
101-M816-100UG
About this Product
SKU:
101-M816
Additional Names:
Nidogen-1, NID-1, Entactin
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
translate.label.attr.clone:
2R33
Clonality:
Monoclonal
Extra Details:
Nidogen-1 (also entactin) is a 150 kDa, secreted, monomeric glycoprotein that serves as a major linking component of basement membranes. It is synthesized as a 1247 amino acid (aa) precursor with a 28 aa signal sequence and a 1219 aa mature protein. The molecule is modular in structure with five distinct regions. Functionally, G1 is reported to bind type IV collagen. The mucin region contains a short peptide that ligates alpha 3 beta 1 integrins. G2 interacts with perlecan, and an RGD motif in the rod-shaped segment serves as a binding site for alpha v beta 3 integrins. Finally, G3 is associated with laminin binding.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Recombinant Human Nidogen-1/Entactin
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody