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Antibodies

IL-26

Product Sizes
100 ug
£674.12
101-M786-100UG
About this Product
SKU:
101-M786
Additional Names:
Interleukin-26, Protein AK155
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
6D20
Clonality:
Monoclonal
Extra Details:
Interleukin-26 (IL-26) is a protein that in humans is encoded by the IL26 gene. IL-26 is the most recently identified member of the IL-20 cytokine subfamily,which was formed according to the usage of common receptor subunits and similarities in target-cell profiles and functions. All cytokines belonging to this subfamily are members of the larger IL-10 family. IL-26 is expressed in certain herpesvirus-transformed T cells but not in primary stimulated T cells. IL-26 signals through a receptor complex comprising two distinct proteins called IL-20 receptor 1 and IL-10 receptor 2. By signaling through this receptor complex, IL-26 induces rapid phosphorylation of the transcription factors STAT1 and STAT3, which enhance IL-10 and IL-8 secretion and as expression of the CD54 molecule on the surface of epithelial cells.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Human recombinant IL-26
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody