IL-24
Product Sizes
100 ug
£674.12
101-M785-100UG
About this Product
- SKU:
- 101-M785
- Additional Names:
- interleukin 24; C49A; FISP; MDA7; MOB5; ST16; IL10B
- Application:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 6F48
- Clonality:
- Monoclonal
- Extra Details:
- IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Human recombinant IL-24
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody