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Antibodies

IL-24

Product Sizes
100 ug
£674.12
101-M785-100UG
About this Product
SKU:
101-M785
Additional Names:
interleukin 24; C49A; FISP; MDA7; MOB5; ST16; IL10B
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
6F48
Clonality:
Monoclonal
Extra Details:
IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Human recombinant IL-24
Isotype:
IgG2
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody