IL-17 (CTLA-8)
Product Sizes
100 ug
£674.12
101-M783-100UG
About this Product
- SKU:
- 101-M783
- Additional Names:
- IL17A; IL17; CTLA8; IL-17; IL-17A
- Application:
- Block/Inhibit/Neutralise, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 9J17
- Clonality:
- Monoclonal
- Extra Details:
- The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Human recombinant CTLA-8 (IL-17)
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody