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Antibodies

MCP-4

Product Sizes
500 ug
£370.59
101-M76-500UG
About this Product
SKU:
101-M76
Additional Names:
CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
Application:
Block/Inhibit/Neutralise, ELISA, Western Blot
Buffer:
PBS
Clonality:
Monoclonal
Extra Details:
Monocyte Chemoattractant Protein-4 (MCP-4), is a CC chemokine that acts as a chemoattractant for monocytes, eosinophils and T cells and as an activator of basophils. Human MCP-4/CCL13 cDNA encodes a 98 amino acid residue precursor protein with a 23 amino acid residue hydrophobic signal peptide that is cleaved to yield an 8 kDa, 75 aa mature CCL13. Mature MCP-4 lacks any potential N-glycosylation sites and shares a pyroglutamate proline motif with other human MCP proteins. Human MCP-4 is most homologous to MCP-1, -3 and Eotaxin, exhibiting approximately 65-66% amino acid sequence identity. CCL13 or MCP-4 mRNA is expressed by a number of activated cell types, including endothelial cells, macrophages, bronchial epithelium and type II alveolar cells, and perhaps lymphocytes. The bioactivities of MCP-4 are mediated by the CC chemokine receptors CCR2 and CCR3.
Formulation:
lyophilized from PBS
Host:
Mouse
Immunogen:
Recombinant Human MCP-4
Isotype:
IgG1, kappa
Purification:
Protein A Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody