Gi24 (B7-H5, VISTA, PD-1H)
Product Sizes
100 ug
£674.12
101-M758-100UG
About this Product
- SKU:
- 101-M758
- Additional Names:
- V-type immunoglobulin domain-containing suppressor of T-cell activation, Platelet receptor Gi24, Stress-induced secreted protein-1 (Sisp-1), V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor
- Application:
- Flow Cytometry, Immunocytochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 29N17
- Clonality:
- Monoclonal
- Extra Details:
- VISTA (V-domain immunoglobulin suppressor of T cell activation) is an immune checkpoint receptor expressed primarily on the surface of hematopoietic cells. Specifically, VISTA is expressed on naive CD4+ T cells and regulatory T cells. And it is up regulated in vivo on activated monocytes and dendritic cells. VISTA inhibits CD4+ and CD8+ T cell proliferation, and their production of the proinflammatory cytokines IL 2 and IFN gamma. VISTA protein is also observed on the surface of cancer cells and attenuates the anti tumor immune response enabling tumor progression. VISTA, also known as B7 H5, PD-1H, Platelet receptor Gi24, Dies1, and SISP1, is a 55 65 kDa transmembrane glycoprotein with homology to B7 like immune co stimulatory molecules.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant human Gi24 (B7-H5, VISTA, PD-1H)
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody