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Antibodies

Galectin-7

Product Sizes
100 ug
£674.12
101-M748-100UG
About this Product
SKU:
101-M748
Additional Names:
Gal-7, HKL-14, PI7, p53-induced gene 1 protein
Application:
Flow Cytometry, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
3G35
Clonality:
Monoclonal
Extra Details:
Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and supra-basal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the supra-basal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and it's striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
Formulation:
lyophilized
Host:
Mouse
Immunogen:
Recombinant human Galectin-7
Isotype:
IgG1
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Ambient
Storage Conditions:
-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:
ReliaTech
Type:
Antibody: Monoclonal Antibody