MMP-17
Product Sizes
100 ug
£674.12
101-M714-100UG
About this Product
- SKU:
- 101-M714
- Additional Names:
- Matrix metalloproteinase-17; Membrane-type matrix metalloproteinase 4, Membrane-type-4 matrix metalloproteinase
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- 12N24
- Clonality:
- Monoclonal
- Extra Details:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage and is known to be expressed in brain, leukocytes, colon, ovary testis and breast cancer as well as in many transformed and non-transformed cell types. The protein exists in two isoforms: a GPI-anchored form and a second secreted form.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant human MMP-17
- Isotype:
- IgG2
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody